PEG MGF 2mg × 10 vials

PEG MGF 2mg × 10 vials offers extended half-life for studies on muscle repair and anabolic effects.

PEG-MGF 2mg × 10 Vials delivers a pegylated formulation of Mechano Growth Factor (MGF) engineered for prolonged biological activity in research settings. Each vial contains 2 mg of high-purity, lyophilized PEG-MGF, with a total of 10 vials per package. The PEG modification helps slow degradation and extend effective duration of action.

What is PEG-MGF?
MGF (also known as IGF-1 Ec) is a splice variant of IGF-1 released in response to mechanical stress, playing a central role in activating muscle satellite cells and promoting repair. However, native MGF is rapidly degraded (short half-life). Pegylation—the covalent attachment of polyethylene glycol (PEG)—is used to enhance stability, reduce clearance, and prolong the peptide’s presence in biological systems. Core Peptides+2cooperpharma.com+2

Mechanism & Research Rationale

• The PEG moiety helps the peptide remain in circulation longer, prolonging regenerative signaling. cooperpharma.com+2Biotech Peptides+2

• In muscle injury or stress models, PEG-MGF is hypothesized to better support satellite cell activation, muscle repair, and protein synthesis compared to unmodified MGF. Biotech Peptides+2Core Peptides+2

• Emerging animal and cell studies also explore its possible roles in cartilage repair, bone healing, and connective tissue regeneration. PMC+3Core Peptides+3cooperpharma.com+3

Key Features & Specifications

• Strength: 2 mg PEG-MGF per vial, 10 vials total

• Purity: High research-grade quality

• Format: Lyophilized powder (sterile)

• Intended Use: Research / Laboratory only (not for human or veterinary use)

• Quality Control: Validated by HPLC / Mass Spectrometry

• Storage: Keep at –20 °C (or follow institutional protocol)

• Reconstitution: Use sterile buffer prior to assays or experiments

Applications in Research

• Muscle Regeneration & Recovery: Studying prolonged signaling effects and satellite cell dynamics

• Tissue Engineering & Biomaterials: Incorporating PEG-MGF in scaffolds for sustained growth factor delivery

• Cartilage & Connective Tissue Studies: Evaluating effects on chondrocytes, fibroblasts, and joint repair models Core Peptides+1

• Bone & Osteogenesis Research: Investigating osteoblast proliferation and bone defect repair PMC+2Core Peptides+2

• Comparative Signaling & Kinetics: Contrast PEG-MGF vs native MGF (short half-life) in temporal response studies

Related Products
For comparative or complementary studies, consider:

• MGF 2mg × 10 Vials – the non-pegylated, short-acting form

• Cagrilintide + Semaglutide 10mg × 10 Vials – for metabolic or endocrine pathway research

Safety & Use Disclaimer
This product is intended strictly for research use only. It is not approved for human or veterinary use, diagnostic, or therapeutic applications. Users must adhere to institutional safety guidelines, regulatory policies, and proper sterile handling processes.