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FOX04 10mg × 10 vials
$230.00
FOX04 10mg peptide × 10 vials for senescence and aging studies.
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Buy FOX04 10mg × 10 Vials Online
FOX04 peptide is used in research focused on cell senescence and aging mechanisms.
FOXO4-DRI is a synthetic D-retro-inverso peptide designed to selectively induce apoptosis in senescent cells. By disrupting the interaction between FOXO4 and p53 proteins, FOXO4-DRI facilitates the elimination of dysfunctional cells that contribute to aging and age-related diseases. This peptide is supplied as a high-purity lyophilized powder in sealed sterile vials, intended strictly for controlled laboratory studies.
Mechanism & Research Rationale
Under normal conditions, FOXO4 binds to p53, preventing it from inducing apoptosis in senescent cells. FOXO4-DRI disrupts this interaction, allowing p53 to initiate programmed cell death in dysfunctional cells. This selective elimination of senescent cells has been shown to restore tissue function and improve overall health in animal models.
Key Features & Specifications
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Strength: 10 mg per vial × 10 vials
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Purity: ≥99% by HPLC-MS
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Format: Lyophilized powder, sterile
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Quality Assurance: Certificate of Analysis (COA) available
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Intended Use: In vitro and preclinical research only
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Storage: Store lyophilized at –20 °C; reconstituted at 2–8 °C and use within 28 days
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Handling: Reconstitute with sterile water or buffer per laboratory protocols
Applications in Research
FOXO4-DRI is utilized in various research areas, including:
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Aging and Cellular Senescence: Investigating the role of senescent cells in aging and age-related diseases.
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Cancer Research: Studying the impact of senescent cells on tumor progression and therapy resistance.
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Tissue Regeneration: Exploring the potential of FOXO4-DRI in enhancing tissue repair and regeneration.
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Endocrine Function: Assessing the effects of FOXO4-DRI on hormone secretion and related pathways.
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Safety & Disclaimer
This product is intended for research use only. It is not intended for human or veterinary consumption, diagnosis, or therapeutic use. Users must adhere to institutional safety protocols, regulatory guidelines, and handle under sterile, controlled conditions.
