Cagrilintide 10mg + Semaglutide 10mg 10mg × 10 vials

Cagrilintide 10mg + Semaglutide 10mg 10mg × 10 vials is used in advanced research for diabetes, obesity, and metabolic syndrome.

Overview

The Cagrilintide + Semaglutide 10 mg × 10 Vials is a high-purity peptide combination designed for advanced research in metabolic, obesity, and endocrinology studies. This dual-hormone formulation merges Cagrilintide, an amylin analog, with Semaglutide, a GLP-1 receptor agonist, offering synergistic effects on appetite regulation, glucose metabolism, and weight management.

Mechanism & Research Rationale

Dual-Hormone Synergy

• Semaglutide functions by slowing gastric emptying, reducing glucagon secretion, and enhancing insulin release in a glucose-dependent manner.

• Cagrilintide, as an analog of amylin, further enhances satiety and prolongs gastric retention via signaling in the hindbrain and brainstem.
  Together, they engage overlapping and complementary pathways to suppress appetite, improve metabolic control, and amplify weight reduction effects. the-innovation.org+2ScienceDirect+2
  Clinical trials (e.g. REDEFINE) have shown that co-administration of cagrilintide and semaglutide leads to significantly greater weight loss compared to monotherapy arms. PubMed+2New England Journal of Medicine+2

Clinical Evidence
In the landmark REDEFINE-1 Phase III trial, participants receiving the combined cagrilintide-semaglutide treatment achieved mean weight reductions exceeding 20% over 68 weeks—substantially more than placebo and monotherapy groups. PubMed+2ADA Meeting News+2
This potent efficacy supports its potential for translational research into obesity, diabetes, and metabolic disease interventions. ADA Meeting News+1

Features & Specifications

• Quantity & Strength: 10 vials of 10 mg each

• Purity: ≥ 99% (HPLC / MS-verified in cGMP environments)

• Format: Lyophilized peptide in sterile vials

• Intended Use: Research / laboratory applications (non-therapeutic)

• Stability & Storage: Store at –20 °C (or per lab protocol) and reconstitute prior to use

Applications

• Obesity & Metabolic Research: Model dual-agonist interventions in preclinical systems.

• Endocrine / Appetite Studies: Examine cross-talk between GLP-1, amylin, and central appetite circuits.

• Pharmacokinetics & Dose Optimization: Use in formulation design, PK/PD modeling, or dose titration experiments.

• Mechanistic Studies: Probe receptor signaling, receptor desensitization, or feedback modulation in obesity models.

Safety & Use Disclaimer

This product is supplied strictly for research and development purposes. It is not intended for human or veterinary use. Always follow your institutional biosafety and research protocol standards.
Users must ensure proper handling, sterility, and compliance with applicable laws in their region.